| Constance of York | f ~1374 | d 1416 | |
| & Thomas le Despenser | f 1373 | d 1400 | |
| Elizabeth le Despenser | d ~1398 | ||
| Richard le Despenser | f 1396 | d 1414 | |
| Edward le Despenser | f <1400 | ||
| Hugh le Despenser | f ~1400 | d 1401 | |
| Isabel le Despenser | f 1400 | d 1439 | |
| & Richard de Beauchamp | f 1394 | d 1422 | |
| Elizabeth de Beauchamp | f 1415 | ||
| & Richard de Beauchamp | f 1382 | d 1439 | |
| Henry de Beauchamp | f 1425 | d 1446 | |
| Anne de Beauchamp | f 1426 | d 1492 | |
| & Richard Neville | f 1428 | d 1471 | |
| Isabel Neville | f 1451 | d 1476 | |
| & George of York | f 1449 | d 1478 | |
| Anne Neville | f 1456 | d 1485 | |
| & Edward of Westminster | f 1453 | d 1471 | |
| & Richard III of England | f 1452 | d 1485 | |
| Edward of Middleham | f ~1474 | d 1484 |
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